Life Diagnostics, Inc. adds a new thymidine kinase 1 (TK1) assay to its extensive lineup of SPARCL assays. The new assay was developed for cows (TK1-SP-11), and joins TK1 SPARCL assays previously developed for cats (TK1-SP-8), dogs (TK1-SP-4), and humans (TK1-SP-20).
Thymidine kinase 1 (TK1) is an enzyme involved in DNA synthesis. Its expression levels increase in tissues such as tumors that are proliferating. Upon tumor cell death and lysis, TK1 is released into serum.
- In cows, TK1 enzyme activity has been associated with leukosis.
- In cats, TK1 is a potential biomarker for lymphoma.
- In dogs, it provides a biomarker for lymphoma and mammary tumors.
- In humans, TK1 provides a biomarker for tumor growth and metastasis.
In addition to fully developed and tested SPARCL assay kits, Life Diagnostics provides HRP and acridan conjugation services for the development of new SPARCL assays. Please visit the Life Diagnostics SPARCL Assay web page for more information.
